Prof. Bernhard Kräutler

em. o.Univ.-Prof. Dr. Bernhard Kräutler

Institute of Organic Chemistry
University of Innsbruck
Innrain 80/82
6020 Innsbruck, Austria

tel: +43-512-507-57722
fax: +43-512-507-57799

bernhard kräutler



our main research interests

Our main research interests concern the ‘Pigments of Life’: their discovery in Nature, their chemical and biological synthesis, their structures and their biologically important chemical reactivity. These insights are used in investigations of their biological functions, based on which, we are interested in corresponding applications in the life sciences and in medicine.

research areas

B12 - the Organometallic Cofactor

Chlorophyll Breakdown

Functionalized fullerenes and porphyrins

The Kräutler group is a member of the ‘Center for Molecular Biosciences Innsbruck’ (CMBI).



recent publications

Chengjie Li, Klaus Wurst, Steffen Jockusch, Karl Gruber,
Maren Podewitz, Klaus R. Liedl, Bernhard Kräutler
Chlorophyll-Derived Yellow Phyllobilins of Higher Plants are Medium-Responsive,
Chiral Photoswitches

Angew. Chem. Int. Ed. 55, 15760-15765, (2016)

F. J. Widner, A. D. Lawrence, E. Deery, D. Heldt, S. Frank,
K. Gruber, K. Wurst, M. J. Warren, B. Kräutler
Total Synthesis, Structure and Biological Activity of Adenosylrhodibalamin -
the Nonnatural Rhodium Homologue of Coenzyme B12

Angew. Chem. Int. Ed. 55, 11281-11289, (2016)

B. Kräutler
Breakdown of Chlorophyll in Higher Plants - Phyllobilins as Abundant, Yet Hardly Visible Signs
of Ripening, Senescence and Cell Death (Review)

Angew. Chem. Int. Ed., 55, 4882-4907(2016), Angew. Chem., 128, 4964-4990 (2016)

I. Süssenbacher, S. Hörtensteiner, B. Kräutler
A Dioxobililn-Type Fluorescent Chlorophyll Catabolite as a Transient Early Intermediate
of the Dioxobilin-Branch of Chlorophyll Breakdown in Arabidopsis thaliana

Angew. Chem. Int. Ed., 54, 13777-13781(2015), Angew. Chem., 127, 13981-13985 (2015)

B. Kräutler
Antivitamins B12 - A Structure- and Reactivity-Based Concept
Chem. Eur. J., 21, 11280-11287 (2015)

M. Ruetz, C. Gherasim, K. Gruber, S. Fedosov, R. Banerjee, B. Kräutler
Radical Synthesis Opens Access to Organometallic Aryl-Cobaltcorrins: 4-Ethylphenylcobalamin,
a Potential “Antivitamin B12”

Angew. Chem. Int. Ed., 52, 2606-2610 (2013), Angew. Chem., 125, 2668-2672 (2013)

S. Banala, R. G. Huber, T. Müller, M. Fechtel, K. R. Liedl, B. Kräutler
Porphyrin-LEGO: Synthesis of a Hexafullereno-Diporphyrin Using Porphyrins Programmed for

ChemComm, 48, 4359-4361 (2012)

K. Gruber, B. Puffer, B. Kräutler
Vitamin B12-derivates – enzyme cofactors and ligands of proteins and nucleic acids
Chem. Soc. Rev., 40, 4346 – 4363 (2011)

S. Moser, T. Müller, A. Holzinger, C. Lütz, S. Jokusch, N. J. Turro, B. Kräutler
Fluorescent chlorophyll catabolites in bananas light up blue halos of cell death
Proc. Natl. Acad. Sci., USA 106, 15538-15542 (2009)

S. Banala, T. Rühl, K. Wurst & B. Kräutler
'Blackening' Porphyrins by Conjugating with Quinones
Angew. Chem. Int. Ed. 48, 599-603 (2009), Angew. Chem. 121, 607-611 (2009)

publications curriculum vitae professional activities key lectures


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